Doxycycline: Difference between revisions
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imported>Robert Badgett (New page: Doxycycline is "a synthetic tetracycline derivative with similar antimicrobial activity. Animal studies suggest that it may cause less tooth staining than other tetracyclines. It is used i...) |
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Doxycycline is "a synthetic tetracycline derivative with similar antimicrobial activity. Animal studies suggest that it may cause less tooth staining than other tetracyclines. It is used in some areas for the treatment of chloroquine-resistant falciparum malaria".<ref>{{cite web |url=http://www.nlm.nih.gov/cgi/mesh/2007/MB_cgi?term=Doxycycline |title=Doxycycline|author=National Library of Medicine |accessdate=2007-11-08 |format= |work=}}</ref> | Doxycycline is "a synthetic tetracycline derivative with similar antimicrobial activity. Animal studies suggest that it may cause less tooth staining than other tetracyclines. It is used in some areas for the treatment of chloroquine-resistant falciparum malaria".<ref>{{cite web |url=http://www.nlm.nih.gov/cgi/mesh/2007/MB_cgi?term=Doxycycline |title=Doxycycline|author=National Library of Medicine |accessdate=2007-11-08 |format= |work=}}</ref> | ||
==Pharmacokinetics== | |||
===Absorption=== | |||
Immediate-release formulations of doxycycline, similar to tetracycline<ref name="pmid3838321">{{cite journal |author=Leyden JJ |title=Absorption of minocycline hydrochloride and tetracycline hydrochloride. Effect of food, milk, and iron |journal=J. Am. Acad. Dermatol. |volume=12 |issue=2 Pt 1 |pages=308–12 |year=1985 |pmid=3838321 |doi=}}</ref>, has absorption affected by milk.<ref name="pmid2767766">{{cite journal |author=Meyer FP, Specht H, Quednow B, Walther H |title=Influence of milk on the bioavailability of doxycycline--new aspects |journal=Infection |volume=17 |issue=4 |pages=245–6 |year=1989 |pmid=2767766 |doi=}}</ref> | |||
===Distribution=== | |||
===Metabolism=== | |||
===Excretion=== | |||
==Medical uses== | ==Medical uses== | ||
Revision as of 08:23, 9 November 2007
Doxycycline is "a synthetic tetracycline derivative with similar antimicrobial activity. Animal studies suggest that it may cause less tooth staining than other tetracyclines. It is used in some areas for the treatment of chloroquine-resistant falciparum malaria".[1]
Pharmacokinetics
Absorption
Immediate-release formulations of doxycycline, similar to tetracycline[2], has absorption affected by milk.[3]
Distribution
Metabolism
Excretion
Medical uses
References
- ↑ National Library of Medicine. Doxycycline. Retrieved on 2007-11-08.
- ↑ Leyden JJ (1985). "Absorption of minocycline hydrochloride and tetracycline hydrochloride. Effect of food, milk, and iron". J. Am. Acad. Dermatol. 12 (2 Pt 1): 308–12. PMID 3838321. [e]
- ↑ Meyer FP, Specht H, Quednow B, Walther H (1989). "Influence of milk on the bioavailability of doxycycline--new aspects". Infection 17 (4): 245–6. PMID 2767766. [e]