Stavudine: Difference between revisions
imported>David E. Volk (Chem infobox) |
mNo edit summary |
||
| (2 intermediate revisions by 2 users not shown) | |||
| Line 6: | Line 6: | ||
|molname=stavudine | |molname=stavudine | ||
|synonyms= '''Zerit®''' | |synonyms= '''Zerit®''' | ||
|molformula= C<sub> | |molformula= C<sub>10</sub>H<sub>12</sub>N<sub>2</sub>O<sub>4</sub> | ||
|molmass= 224.2133 | |molmass= 224.2133 | ||
|uses=HIV/AIDS | |uses=HIV/AIDS | ||
| Line 23: | Line 23: | ||
== External links == | == External links == | ||
{{CZMed}}[[Category:Suggestion Bot Tag]] | |||
Latest revision as of 07:01, 22 October 2024
|
| |||||||
| stavudine | |||||||
| |||||||
| Uses: | HIV/AIDS | ||||||
| Properties: | thymidine-like RT inhibitor | ||||||
| Hazards: | see Drug interactions | ||||||
| |||||||
Stavudine is a dideoxynucleoside analog (2',3'-Didehydro-3'-deoxythymidine) , antiviral drug that inhibits reverse transcriptase and is used to treat against HIV/AIDS sold under the brand name Zerit®. It is in the drug class nucleoside reverse transcriptase inhibitor (NRTI). The phosphorylated form is the active compound that competes with deoxythymidine triphosphate (dTTP) for incorporation into the viral DNA and which acts as a DNA chain terminator once so incorporated due to the lack of a 3'-hydroxy group.
Chemistry
The IUPAC chemical name for stavudine is 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione, and it has a molecular formula C10H12N2O4, giving it a molecular mass of 224.2133 g/mol.
External links
The most up-to-date information about Stavudine and other drugs can be found at the following sites.
- Stavudine - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Stavudine - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
- Stavudine - Detailed information from DrugBank.