Methotrexate/Definition: Difference between revisions
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An inhibitor of [[tetrahydrofolate dehydrogenase]], which prevents the formation of [[tetrahydrofolate]], necessary for synthesis of [[thymidylate]], an essential component of [[DNA]] | An inhibitor of [[tetrahydrofolate dehydrogenase]], which prevents the formation of [[tetrahydrofolate]], necessary for synthesis of [[thymidylate]], an essential component of [[DNA]]; it has a wide range of medical applications. | ||
Latest revision as of 10:50, 28 December 2010
An inhibitor of tetrahydrofolate dehydrogenase, which prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA; it has a wide range of medical applications.