Protease inhibitor: Difference between revisions
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imported>David E. Volk |
imported>David E. Volk m (→protease inhibitors used to treat HIV/AIDS: Indinavir) |
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== protease inhibitors used to treat [[HIV]]/[[AIDS]] == | == protease inhibitors used to treat [[HIV]]/[[AIDS]] == | ||
* [[amprenavir]] | * [[amprenavir]] | ||
* [[indinavir]] | |||
* [[nelfinavir]] | * [[nelfinavir]] | ||
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* [[Saquinavir]] | * [[Saquinavir]] | ||
== Other protease inhibitors == | == Other protease inhibitors == | ||
* [[Acyclovir]] is use to treate herpes and chickpox infections | * [[Acyclovir]] is use to treate herpes and chickpox infections | ||
Revision as of 10:23, 29 January 2008
A protease inhibitor is a chemical compound that inhibits the functions of proteases to control viral infections, especially so for the treatment of HIV/AIDS, but also for the treatment of other viruses, such as chicken pox. All cells have protease enzymes that cleave cellular proteins, which are required for normal cell live cycles. By distrupting the use of natural proteases within the cell, the use of protease inhibitors causes severe side effects, and because the half-life of many protease inhibitors is short (3-5 hr.), the drugs must be taken every 4-6 hours. Protease inhibitors are often structural mimics of protein active (binding) sites on which the proteases would normally bind.
protease inhibitors used to treat HIV/AIDS
Other protease inhibitors
- Acyclovir is use to treate herpes and chickpox infections