Salmonella enterica: Difference between revisions

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==Pathology==
==Pathology==
How does this organism cause disease?  Human, animal, plant hosts?  Virulence factors, as well as patient symptoms.
Different species of Salmonella can cause a wide range of diseases from gastrointestinal problems to typhoid fever. ''S. typhi,'' a serovar of ''S. enterica,'' will only infect humanans. The typhoid fever that it caused kills 500,000 people per year. Other serovars like ''S. typhimurium'' infect humans, as well as many other mammalian species. The bacteria enters the host by disturbing the membrane. Once inside, it harms the host by causing the levels of intracellular free calcium to increase and disorganizing the cytoplasm of the cell. Symptoms usually include diarrhea, fever, and abdominal cramps. Strains that are associated with food-borne infections are usually not treated with antibiotics, but will resolve themselves over time. The typhoidal strains usually do require treatment by antibiotics, and possibly hospitilization. Some of the antibiotics have been used in the beef and poultry industries. This has caused for a strain of bacteria to be resistant to the antibiotics.


==Application to Biotechnology==
==Application to Biotechnology==

Revision as of 19:39, 25 March 2008

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Classification

Tosco Refinery.jpg

Higher order taxa

Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae

Species

Salmonella enterica

Description and significance

Salmonella enterica are rod shaped gram-negative bacteria. They are very commonly found in raw meat, chicken, and egg shells. Another one of its' habitats is in contaminated water. A famous example of one its' 2000 serovars is S. typhi, the cause of typhoid fever. Research done on the genomic sequencing of S. enterica can aid in the effectiveness of medications and vaccinations in treating disease. It is usually isolated on a selective medium such as Maconkey agar, XLD agar, XLT agar, or DCA agar.

Genome structure

Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?

Cell structure and metabolism

S. enterica is a motile, rod shaped bacteria that contain flagella.

Ecology

Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.

Pathology

Different species of Salmonella can cause a wide range of diseases from gastrointestinal problems to typhoid fever. S. typhi, a serovar of S. enterica, will only infect humanans. The typhoid fever that it caused kills 500,000 people per year. Other serovars like S. typhimurium infect humans, as well as many other mammalian species. The bacteria enters the host by disturbing the membrane. Once inside, it harms the host by causing the levels of intracellular free calcium to increase and disorganizing the cytoplasm of the cell. Symptoms usually include diarrhea, fever, and abdominal cramps. Strains that are associated with food-borne infections are usually not treated with antibiotics, but will resolve themselves over time. The typhoidal strains usually do require treatment by antibiotics, and possibly hospitilization. Some of the antibiotics have been used in the beef and poultry industries. This has caused for a strain of bacteria to be resistant to the antibiotics.

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?

Current Research

Enter summaries of the most recent research here--at least three required

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.