Troponin: Difference between revisions
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'''Troponin''' is a protein of | '''Troponin''' is a protein of muscle, blood levels of which have become important in diagnosis. "Its function is to serve as the calcium-binding component in the troponin-tropomyosin B-actin-myosin complex by conferring calcium sensitivity to the cross-linked actin and myosin filaments.<ref>{{MeSH}}</ref> | ||
Troponin levels have become an important diagnostic tool in assessing [[acute coronary syndrome]]. | "Cardiac troponins are regulatory proteins of the thin actin filaments of the cardiac muscle. Troponin T and troponin I are highly sensitive and specific markers of myocardial injury."<ref name=>{{citation | ||
| title = Raised cardiac troponins: Causes extend beyond acute coronary syndromes | |||
| journal = BMJ | |||
| date = 2004 May 1 | |||
| volume = 328 | issue = 7447 | pages = 1028–1029. | |||
| doi = 10.1136/bmj.328.7447.1028 | |||
| author = Ammann P ''et al.'}}</ref> Troponin levels have become an important diagnostic tool in assessing [[acute coronary syndrome]], but it is dangerous to assume that ACS is the only reason they may be elevated. | |||
==References== | |||
{{reflist}} | |||
Revision as of 13:44, 13 June 2009
Troponin is a protein of muscle, blood levels of which have become important in diagnosis. "Its function is to serve as the calcium-binding component in the troponin-tropomyosin B-actin-myosin complex by conferring calcium sensitivity to the cross-linked actin and myosin filaments.[1]
"Cardiac troponins are regulatory proteins of the thin actin filaments of the cardiac muscle. Troponin T and troponin I are highly sensitive and specific markers of myocardial injury."[2] Troponin levels have become an important diagnostic tool in assessing acute coronary syndrome, but it is dangerous to assume that ACS is the only reason they may be elevated.
References
- ↑ Anonymous (2024), Troponin (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Ammann P et al.' (2004 May 1), "Raised cardiac troponins: Causes extend beyond acute coronary syndromes", BMJ 328 (7447): 1028–1029., DOI:10.1136/bmj.328.7447.1028