Henoch-Schonlein purpura: Difference between revisions
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In [[medicine]], '''Henoch-Schonlein purpura''' is [[vasculitis]] and [[immune complex disease]] that is "systemic non-thrombocytopenic purpura caused by [[hypersensitivity vasculitis]] and deposition of IGA-containing [[immune complexe]]s within the blood vessels throughout the body, including those in the kidney ([[kidney glomerulus]]). Clinical symptoms include [[urticaria]]; [[erythema]]; [[arthritis]]; [[gastrointestinal hemorrhage]]; and renal involvement. Most cases are seen in children after acute upper respiratory infections."<ref>{{MeSH}}</ref> | {{subpages}} | ||
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In [[medicine]], '''Henoch-Schonlein purpura''' is a [[vasculitis]] and [[immune complex disease]] that is "systemic non-thrombocytopenic purpura caused by [[hypersensitivity vasculitis]] and deposition of IGA-containing [[immune complexe]]s within the blood vessels throughout the body, including those in the kidney ([[kidney glomerulus]]). Clinical symptoms include [[urticaria]]; [[erythema]]; [[arthritis]]; [[gastrointestinal hemorrhage]]; and renal involvement. Most cases are seen in children after acute upper respiratory infections."<ref>{{MeSH}}</ref> | |||
It may be associated with bacteremia from ''[[Staphylococcus aureus]]''.<ref name="pmid16807418">{{cite journal| author=Denton MD, Digumarthy SR, Chua S, Colvin RB| title=Case records of the Massachusetts General Hospital. Case 20-2006. An 84-year-old man with staphylococcal bacteremia and renal failure. | journal=N Engl J Med | year= 2006 | volume= 354 | issue= 26 | pages= 2803-13 | pmid=16807418 | |||
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&retmode=ref&cmd=prlinks&id=16807418 | doi=10.1056/NEJMcpc069012 }} </ref> | | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&retmode=ref&cmd=prlinks&id=16807418 | doi=10.1056/NEJMcpc069012 }} </ref> | ||
Revision as of 01:36, 21 September 2010
In medicine, Henoch-Schonlein purpura is a vasculitis and immune complex disease that is "systemic non-thrombocytopenic purpura caused by hypersensitivity vasculitis and deposition of IGA-containing immune complexes within the blood vessels throughout the body, including those in the kidney (kidney glomerulus). Clinical symptoms include urticaria; erythema; arthritis; gastrointestinal hemorrhage; and renal involvement. Most cases are seen in children after acute upper respiratory infections."[1]
It may be associated with bacteremia from Staphylococcus aureus.[2]
Henoch-Schonlein purpura was the diagnosis on the episode Open and Shut of House.[3]
Treatment
Short terms corticosteroids may help renal disease.[4]
References
- ↑ Anonymous (2024), Henoch-Schonlein purpura (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Denton MD, Digumarthy SR, Chua S, Colvin RB (2006). "Case records of the Massachusetts General Hospital. Case 20-2006. An 84-year-old man with staphylococcal bacteremia and renal failure.". N Engl J Med 354 (26): 2803-13. DOI:10.1056/NEJMcpc069012. PMID 16807418. Research Blogging.
- ↑ (2010) Open and Shut
- ↑ Chartapisak W, Opastirakul S, Hodson EM, Willis NS, Craig JC (2009). "Interventions for preventing and treating kidney disease in Henoch-Schönlein Purpura (HSP).". Cochrane Database Syst Rev (3): CD005128. DOI:10.1002/14651858.CD005128.pub2. PMID 19588365. Research Blogging.