Anti-Ro: Difference between revisions
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'''Anti-Ro autobody''', also called '''anti-SS-A''', is associatied with [[connective tissue disease]], such as [[Sjogren's syndrome]] and [[systemic lupus erythematosus]], and [[vasculitis]]. | '''Anti-Ro autobody''', also called '''anti-SS-A''', is associatied with [[connective tissue disease]], such as [[Sjogren's syndrome]] and [[systemic lupus erythematosus]], and [[vasculitis]]. | ||
Of patients without known illness, 3% will be positive for anti-Ro.<ref name=" | Of patients without known illness, 3% will be positive for anti-Ro.<ref name="pmid14561795">{{cite journal| author=Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA et al.| title=Development of autoantibodies before the clinical onset of systemic lupus erythematosus. | journal=N Engl J Med | year= 2003 | volume= 349 | issue= 16 | pages= 1526-33 | pmid=14561795 | doi=10.1056/NEJMoa021933 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14561795 }} </ref> | ||
Anti-R antibodies may be present three years before development of [[systemic lupus erythematosus]]. <ref name="pmid6600593">{{cite journal| author=Alexander EL, Arnett FC, Provost TT, Stevens MB| title=Sjögren's syndrome: association of anti-Ro(SS-A) antibodies with vasculitis, hematologic abnormalities, and serologic hyperreactivity. | journal=Ann Intern Med | year= 1983 | volume= 98 | issue= 2 | pages= 155-9 | pmid=6600593 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6600593 }} </ref> | Anti-R antibodies may be present three years before development of [[systemic lupus erythematosus]].<ref name="pmid6600593">{{cite journal| author=Alexander EL, Arnett FC, Provost TT, Stevens MB| title=Sjögren's syndrome: association of anti-Ro(SS-A) antibodies with vasculitis, hematologic abnormalities, and serologic hyperreactivity. | journal=Ann Intern Med | year= 1983 | volume= 98 | issue= 2 | pages= 155-9 | pmid=6600593 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6600593 }} </ref> | ||
Patients with anti-Ro have more systematic illness.<ref name=" | Patients with anti-Ro have more systematic illness.<ref name="pmid6600593">{{cite journal| author=Alexander EL, Arnett FC, Provost TT, Stevens MB| title=Sjögren's syndrome: association of anti-Ro(SS-A) antibodies with vasculitis, hematologic abnormalities, and serologic hyperreactivity. | journal=Ann Intern Med | year= 1983 | volume= 98 | issue= 2 | pages= 155-9 | pmid=6600593 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6600593 }} </ref> | ||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 12:24, 27 September 2012
Anti-Ro autobody, also called anti-SS-A, is associatied with connective tissue disease, such as Sjogren's syndrome and systemic lupus erythematosus, and vasculitis.
Of patients without known illness, 3% will be positive for anti-Ro.[1]
Anti-R antibodies may be present three years before development of systemic lupus erythematosus.[2]
Patients with anti-Ro have more systematic illness.[2]
References
- ↑ Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA et al. (2003). "Development of autoantibodies before the clinical onset of systemic lupus erythematosus.". N Engl J Med 349 (16): 1526-33. DOI:10.1056/NEJMoa021933. PMID 14561795. Research Blogging.
- ↑ 2.0 2.1 Alexander EL, Arnett FC, Provost TT, Stevens MB (1983). "Sjögren's syndrome: association of anti-Ro(SS-A) antibodies with vasculitis, hematologic abnormalities, and serologic hyperreactivity.". Ann Intern Med 98 (2): 155-9. PMID 6600593. [e]