Spironolactone: Difference between revisions

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'''Spironolactone''' is an aldosterone antagonist used to treat edema associated with [[congestive heart failure]], [[nephrotic syndrome]] or [[hepatic cirrhosis]].  Although it can also be used treat [[hirsutism]] and [[acne]] by effecting the [[endocrine system]], such use can lead to adverse side effects.
'''Spironolactone''' is an [[aldosterone]] antagonist used to treat [[edema]] associated with [[congestive heart failure]], [[nephrotic syndrome]] or [[hepatic cirrhosis]].  Although it can also be used treat [[hirsutism]] and [[acne]] by effecting the [[endocrine system]], such use can lead to adverse side effects.
Its IUPAC name is S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,
Its IUPAC name is S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,
16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate.
16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate.
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== trade names ==
== trade names ==
Abbolactone  
Abbolactone  
Acelat  
*Acelat  
Aldace  
*Aldace  
Aldactazide  
*Aldactazide  
Aldactide  
*Aldactide  
Aldactone  
*Aldactone  
Aldactone A  
*Aldactone A  
Alderon  
*Alderon  
Aldopur  
*Aldopur  
Almatol  
*Almatol  
Altex  
*Altex  
Aquareduct  
*Aquareduct  
Deverol  
*Deverol  
Diatensec  
*Diatensec  
Dira  
*Dira  
Duraspiron  
*Duraspiron  
Espironolactona [INN-Spanish]  
*Espironolactona [INN-Spanish]  
Euteberol  
*Euteberol  
Lacalmin  
*Lacalmin  
Lacdene  
*Lacdene  
Laractone  
*Laractone  
Melarcon  
*Melarcon  
Nefurofan  
*Nefurofan  
Osyrol  
*Osyrol  
SNL  
*SNL  
Sagisal  
*Sagisal  
Sincomen  
*Sincomen  
Spiresis  
*Spiresis  
Spiretic  
*Spiretic  
Spiridon  
*Spiridon  
Spiro-Tablinen  
*Spiro-Tablinen  
Spiroctan  
*Spiroctan  
Spiroctanie  
*Spiroctanie  
Spiroderm  
*Spiroderm  
Spirolactone  
*Spirolactone  
Spirolakton  
*Spirolakton  
Spirolang  
*Spirolang  
Spirolone  
*Spirolone  
Spirone  
*Spirone  
Spironocompren  
*Spironocompren  
Spironolactone A  
*Spironolactone A  
Spironolactone [BAN:INN:JAN]  
*Spironolactone [BAN:INN:JAN]  
Spironolactonum [INN-Latin]  
*Spironolactonum [INN-Latin]  
Spironolattone [DCIT]  
*Spironolattone [DCIT]  
Sprioderm  
*Sprioderm  
Supra-puren  
*Supra-puren  
Suracton  
*Suracton  
Uractone  
*Uractone  
Urusonin  
*Urusonin  
Verospiron  
*Verospiron  
Verospirone  
*Verospirone  
Verospirone Opianin  
*Verospirone Opianin  
Xenalon  
*Xenalon  


== references ==
== references ==
Material adapted from Drug Bank at (http://redpoll.pharmacy.ualberta.ca/drugbank/cgi-bin/getCard.cgi?CARD=APRD01234)
Material adapted from Drug Bank at (http://redpoll.pharmacy.ualberta.ca/drugbank/cgi-bin/getCard.cgi?CARD=APRD01234)

Revision as of 09:32, 22 January 2008

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Spironolactone is an aldosterone antagonist used to treat edema associated with congestive heart failure, nephrotic syndrome or hepatic cirrhosis. Although it can also be used treat hirsutism and acne by effecting the endocrine system, such use can lead to adverse side effects. Its IUPAC name is S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15, 16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate.

trade names

Abbolactone

  • Acelat
  • Aldace
  • Aldactazide
  • Aldactide
  • Aldactone
  • Aldactone A
  • Alderon
  • Aldopur
  • Almatol
  • Altex
  • Aquareduct
  • Deverol
  • Diatensec
  • Dira
  • Duraspiron
  • Espironolactona [INN-Spanish]
  • Euteberol
  • Lacalmin
  • Lacdene
  • Laractone
  • Melarcon
  • Nefurofan
  • Osyrol
  • SNL
  • Sagisal
  • Sincomen
  • Spiresis
  • Spiretic
  • Spiridon
  • Spiro-Tablinen
  • Spiroctan
  • Spiroctanie
  • Spiroderm
  • Spirolactone
  • Spirolakton
  • Spirolang
  • Spirolone
  • Spirone
  • Spironocompren
  • Spironolactone A
  • Spironolactone [BAN:INN:JAN]
  • Spironolactonum [INN-Latin]
  • Spironolattone [DCIT]
  • Sprioderm
  • Supra-puren
  • Suracton
  • Uractone
  • Urusonin
  • Verospiron
  • Verospirone
  • Verospirone Opianin
  • Xenalon

references

Material adapted from Drug Bank at (http://redpoll.pharmacy.ualberta.ca/drugbank/cgi-bin/getCard.cgi?CARD=APRD01234)