Rosuvastatin: Difference between revisions
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imported>David E. Volk m (type II not class II) |
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[[Image:Rosuvastatin structure.jpg|right|thumb|350px|{{#ifexist:Template:Rosuvastatin structure.jpg/credit|{{Rosuvastatin structure.jpg/credit}}<br/>|}}Rosuvastatin, a | [[Image:Rosuvastatin structure.jpg|right|thumb|350px|{{#ifexist:Template:Rosuvastatin structure.jpg/credit|{{Rosuvastatin structure.jpg/credit}}<br/>|}}Rosuvastatin, a type II statin.]] | ||
'''Rosuvastatin''', marketed as '''Crestor''', is a | '''Rosuvastatin''', marketed as '''Crestor''', is a type II statin used to treat high cholesterol levels ([[hypercholesterolemia]]), prevent [[myocardial infarction|heart attacks]] and [[stroke]]s, and to diminish the formation of [[atherosclerosis|arterial plaque]]. It is a [[Hydroxymethylglutaryl-coenzyme A reductase inhibitor|HMG-CoA reductase inhibitor]] that decreases the conversion of HMG-CoA to [[mevalonate]], a key chemical precursor of [[cholesterol]]. It is related to other type II statins such as [[fluvastatin]] and [[atorvastatin]]. | ||
Its official chemical IUPAC name is (E,3R,5R)-7-[4-(4-fluorophenyl)-2-(methyl-methylsulfonylamino)-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C<sub>22</sub>H<sub>28</sub>FN<sub>3</sub>O<sub>6</sub>S. | Its official chemical IUPAC name is (E,3R,5R)-7-[4-(4-fluorophenyl)-2-(methyl-methylsulfonylamino)-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C<sub>22</sub>H<sub>28</sub>FN<sub>3</sub>O<sub>6</sub>S. | ||
Revision as of 12:53, 24 January 2008
Rosuvastatin, marketed as Crestor, is a type II statin used to treat high cholesterol levels (hypercholesterolemia), prevent heart attacks and strokes, and to diminish the formation of arterial plaque. It is a HMG-CoA reductase inhibitor that decreases the conversion of HMG-CoA to mevalonate, a key chemical precursor of cholesterol. It is related to other type II statins such as fluvastatin and atorvastatin.
Its official chemical IUPAC name is (E,3R,5R)-7-[4-(4-fluorophenyl)-2-(methyl-methylsulfonylamino)-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C22H28FN3O6S.