Porphyrin: Difference between revisions
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'''Porphyrins''' are a "group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the [[heme]] component in biologically significant compounds such as [[hemoglobin]] and [[myoglobin]]."<ref>{{MeSH}}</ref> [[Heme]] is also a component of [[cytochrome P-450]]. | '''Porphyrins''' are a "group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the [[heme]] component in biologically significant compounds such as [[hemoglobin]] and [[myoglobin]]."<ref>{{MeSH}}</ref> [[Heme]] is also a component of [[cytochrome P-450]]. | ||
[[Porphyria]]s are metabolic diseases in the [[heme]] biosynthetic pathway characterized by buildup of | [[Porphyria]]s are metabolic diseases in the [[heme]] biosynthetic pathway characterized by buildup of porphyrin precursors such as porphobilinogen (PBG). | ||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 07:18, 10 September 2008
Porphyrins are a "group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin."[1] Heme is also a component of cytochrome P-450.
Porphyrias are metabolic diseases in the heme biosynthetic pathway characterized by buildup of porphyrin precursors such as porphobilinogen (PBG).
References
- ↑ Anonymous (2024), Porphyrin (English). Medical Subject Headings. U.S. National Library of Medicine.