Parkinson's disease: Difference between revisions
imported>Robert Badgett (New page: In medicine, '''Parkinson disease''', also called '''primary Parkinsonism''', '''Paralysis Agitans''', and other names,is a Parkinsonian disorder that is "a progressive, degenerati...) |
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In [[medicine]], '''Parkinson disease''', also called '''primary Parkinsonism''', '''Paralysis Agitans''', and other names,is a [[Parkinsonian disorder]] that is "a progressive, degenerative neurologic disease characterized by a [[tremor]] that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the [[substantia nigra]] and other pigmented nuclei of the [[brainstem]]. Lewy Bodies are present in the substantia nigra and locus coeruleus but may also be found in a related condition ([[diffuse Lewy Body disease|Lewy Body Disease, diffuse]])) characterized by dementia in combination with varying degrees of parkinsonism."<ref>{{MeSH}}</ref> | In [[medicine]], '''Parkinson disease''', also called '''primary Parkinsonism''', '''Paralysis Agitans''', and other names,is a [[Parkinsonian disorder]] that is "a progressive, degenerative neurologic disease characterized by a [[tremor]] that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the [[substantia nigra]] and other pigmented nuclei of the [[brainstem]]. Lewy Bodies are present in the substantia nigra and locus coeruleus but may also be found in a related condition ([[diffuse Lewy Body disease|Lewy Body Disease, diffuse]])) characterized by dementia in combination with varying degrees of parkinsonism."<ref>{{MeSH}}</ref> | ||
Revision as of 14:39, 26 June 2010
In medicine, Parkinson disease, also called primary Parkinsonism, Paralysis Agitans, and other names,is a Parkinsonian disorder that is "a progressive, degenerative neurologic disease characterized by a tremor that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. Lewy Bodies are present in the substantia nigra and locus coeruleus but may also be found in a related condition (Lewy Body Disease, diffuse)) characterized by dementia in combination with varying degrees of parkinsonism."[1]
Etiology
Some forms of Parkinson disease are inherited[2] via genes such as leucine-rich repeat kinase 2 (LRRK2)[3].
References
- ↑ Anonymous (2024), Parkinson's disease (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Online Mendelian Inheritance in Man, OMIM®. Johns Hopkins University, Baltimore, MD. MIM Number: 168600. World Wide Web URL: http://omim.org/.
- ↑ Online Mendelian Inheritance in Man, OMIM®. Johns Hopkins University, Baltimore, MD. MIM Number: 609007. World Wide Web URL: http://omim.org/.