Hodgkin's disease: Difference between revisions

From Citizendium
Jump to navigation Jump to search
imported>Howard C. Berkowitz
No edit summary
mNo edit summary
 
Line 20: Line 20:
In the classical variant, giant usually multinucleate Hodgkin's and [[Reed-Sternberg cells]], the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
In the classical variant, giant usually multinucleate Hodgkin's and [[Reed-Sternberg cells]], the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
==References==
==References==
{{reflist}}
{{reflist}}[[Category:Suggestion Bot Tag]]

Latest revision as of 17:00, 28 August 2024

This article is developing and not approved.
Main Article
Discussion
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
 
This editable Main Article is under development and subject to a disclaimer.

Also called Hodgkin disease and Hodgkin's lymphoma, Hodgkin's disease is a malignant, but potentially curable, disease of the lymph nodes, spleen, and general lymphoid tissue.

Five variants are defined by the World Health Organization, grouped into two classes:[1]

  • Classical
    • nodular sclerosis
    • mixed cellularity
    • lymphocyte depleted
    • lymphocyte rich
  • nodular lymphocyte predominant Hodgkin disease (NLPHD).

Classical and NLHPD are different clinical entities.[2]

In the classical variant, giant usually multinucleate Hodgkin's and Reed-Sternberg cells, the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.

References

  1. Jaffe ES, Harris NL, Stein H, Vardiman JW, eds. World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2001.
  2. Scott K Dessain, James L Spears, Athanassios Argiris (22 December 2009), "Hodgkin Disease: Overview", eMedicine