Talk:Autism

G'day,

Have imported the Autism article from Wikipedia--it was a decent article at one time but has become a dumping ground for POVs and advocates. I am in a slash and burn mode, deleting large sections of unsourced and not infrequently inane prose. I need help with the data box on the right uppper hand corner if anyone here would like to give me a hand. Let me know what you think we should do with it. Thomas Simmons 13:32, 20 March, 2007 (EPT)

Sources

RE: Thomas Kelly's contribution to section on treatment:

"Removal of heavy metals, like mercury, is one treatments that has been proposed as beneficial to autistic patients."

I have heard of this but have not had a chance to run it down. Do we have a sources for this? Thomas Simmons 13:26, 21 March, 2007 (EPT)

http://www.drhirani.com/weblog2/stories/2005/01/10/autismBiomedicalApproachesToAutism.html I don't have time for more hunting it down. I heard about it originally by her, by mouth. I have not read the paper yet - I am too busy. -Tom Kelly (Talk) 22:49, 20 March 2007 (CDT)

the "paper" is a journal article. (update: still waiting to here which article this is)

This is not an acceptable source, I think you should consider removing the statement Tom, until you or others, come up with something better. In the history of the disease, there have been a very long list of things advocated as "beneficial" for autistic patients, but in this article, these should only be included if there is reasonable evidence that such treatments are efficacious. Nancy Sculerati MD 23:12, 20 March 2007 (CDT)

Other professors, including a very well known immunologist suggested that there may be a link between Hg and autism but nothing can be proven with double-blind studies, obviously, ...and I'm sure it's hard to prove, no matter how well researched. I don't really want to research nutritional articles and articles in French. If you are interested, I'll point you in the direction of some interesting chelating studies in journals. I thought that having qualifiers on the sentence would be enough, but I guess we aren't listing the list of proposed beneficial treatments? ... why not? -Tom Kelly (Talk) 23:56, 20 March 2007 (CDT)

a quick pub med search:

PMID: 17365626 [PubMed - in process]http://zb5lh7ed7a.search.serialssolutions.com/uschsl?sid=Entrez:PubMed&id=pmid:17365626

PMID: 17250511 [PubMed - in process] (against Hg and Autism link)http://www.blackwell-synergy.com/doi/abs/10.1111/j.1442-200X.2007.02303.x

PMID: 17187010 [PubMed - indexed for MEDLINE]Neuro Endocrinol Lett. 2006 Dec;27(6):833-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed

PMID: 17000565 [PubMed - in process]Acta Paediatr Suppl. 2006 Oct;95(453):18-25.

PMID: 17000470 [PubMed - indexed for MEDLINE]Neurotox Res. 2006 Aug;10(1):57-64.

PMID: 16512356 [PubMed - indexed for MEDLINE]Int Rev Neurobiol. 2005;71:317-41.

PMID: 16338635 [PubMed - indexed for MEDLINE]

PMID: 16264412 [PubMed - indexed for MEDLINE]

PMID: 16127438 [PubMed - indexed for MEDLINE]

-Tom Kelly (Talk) 00:12, 21 March 2007 (CDT)

Probably genetic predisposition... probably some trigger, may it be in the uterus, post partum, or another time (auto-immune? virus triggered autoimmune?)... However, since there is so much talk of Hg and Autism, and there is talk about genetic predisposition of being less-able to detoxify metals, and porphyrin studies... it at least deserves a mention. Until proven, I'll continue to use qualifiers. -Tom Kelly (Talk) 00:30, 21 March 2007 (CDT)