Pregabalin

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Revision as of 10:09, 29 February 2008 by imported>David E. Volk (structure pic of pregabalin, gabapentin and GABA)
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Pregabalin and gabapentin are structurally similar to GABA.

Pregabalin is structurally similar to gabapentin. Tt is also similar to the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), and although it does not act on GABA receptors, it may increase the "density of GABA transporter protein and increases the rate of functional GABA transport".[1] It is approved by the for neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia adjunctive therapy for adult patients with partial onset seizures, and fibromyalgia.[1]

References

  1. ↑ 1.0 1.1 Pregabalin - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
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