Cefepime

cefepime
IUPAC name: see chemistry section Synonyms: Formula: C19H24N6O5S2
Uses:	antibiotic drug
Properties:	beta-lactam
Hazards:	see drug interactions
Mass (g/mol): CAS #: 480.5611 88040-23-7

Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. It has more activity than third-generation cephalosporins against Gram-postive and Gram-negative bacteria, and because of this, its use is typically reserved for severe nococomial pneumonia, infections of a multi-resistant bacterial strain and the treatment of febrile neutropenia.

Chemistry

Cefepime has the IUPAC chemical name (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino] -3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, chemical formula C₁₉H₂₄N₆O₅S₂ and molecular mass 480.5611 g/mol. It contains a beta-lactam moiety that is also present in other cephalosporins and penicillins.

Synonyms and brand names

Cefepime is also called cefepima in Spanish and cefepimum in Latin. It is sold under the brand names Maxcef®, Cepimax®, Cepimex® and Axepim®.

External links

• Cefepime - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
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• Template:DrugBank