Antineutrophil cytoplasmic antibodies
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In medicine and rheumatology, antineutrophil cytoplasmic antibodies (ANCA) are "Autoantibodies directed against cytoplasmic constituents of polymorphonuclear leukocytes and/or monocytes. They are used as specific markers for Wegener Granulomatosis and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA."[1]
References
- ↑ Anonymous (2025), Antineutrophil cytoplasmic antibodies (English). Medical Subject Headings. U.S. National Library of Medicine.