Origin of life

An early question that needs to be confronted, indeed a question that in the last analysis requires definition, is: What is life? Most biologists would agree that self-replication, genetic continuity, is a fundamental trait of the life process. Systems that generally would be deemed nonbiological can exhibit a sort of self-replication, however. Examples would be the growth of a crystal lattice or a propagating clay structure. Crystals and clays propagate, unquestionably, but life they are not. There is no locus of genetic continuity, no organism. Such systems do not evolve, do not change in genetic ways to meet new challenges. Consequently, the definition of life should include the capacity for evolution as well as self-replication. Indeed, the mechanism of evolution---natural selection---is a consequence of the necessarily competing drives for self-replication that are manifest in all organisms. The definition based on those processes, then, would be that life is any self-replicating, evolving system (Norman R Pace 2001).

Pre-replicator chemical evolution

Authors/Editors: Consider pre-biotic pre-replicator chemical evolution as prelude to origin of living systems. See, for example:

• Dyson 1982
• Post 1990
• Galimov 2004

References

Further reading

• Vetsigian, K et al. (2006) Collective evolution and the genetic code Proc Natl Acad Sci USA 103:10696–1070. PMID 1681888

• Goldenfeld N Woese C (2007) Essays: Connections. Biology's next revolution The emerging picture of microbes as gene–swapping collectives demands a revision of such concepts as organism, species and evolution itself. Nature 445:369 (25 January 2007) doi:10.1038/445369a

See also

• Life