Henoch-Schonlein purpura

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In medicine, Henoch-Schonlein purpura is a vasculitis and immune complex disease that is "systemic non-thrombocytopenic purpura caused by hypersensitivity vasculitis and deposition of IGA-containing immune complexes within the blood vessels throughout the body, including those in the kidney (kidney glomerulus). Clinical symptoms include urticaria; erythema; arthritis; gastrointestinal hemorrhage; and renal involvement. Most cases are seen in children after acute upper respiratory infections."[1]

It may be associated with bacteremia from Staphylococcus aureus.[2]

Henoch-Schonlein purpura was the diagnosis on the episode Open and Shut of House.[3]

Treatment

Short terms corticosteroids may help renal disease.[4]

References

  1. ↑ Anonymous (2024), Henoch-Schonlein purpura (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. ↑ Denton MD, Digumarthy SR, Chua S, Colvin RB (2006). "Case records of the Massachusetts General Hospital. Case 20-2006. An 84-year-old man with staphylococcal bacteremia and renal failure.". N Engl J Med 354 (26): 2803-13. DOI:10.1056/NEJMcpc069012. PMID 16807418. Research Blogging.
  3. ↑ (2010) Open and Shut
  4. ↑ Chartapisak W, Opastirakul S, Hodson EM, Willis NS, Craig JC (2009). "Interventions for preventing and treating kidney disease in Henoch-Schönlein Purpura (HSP).". Cochrane Database Syst Rev (3): CD005128. DOI:10.1002/14651858.CD005128.pub2. PMID 19588365. Research Blogging.
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