Microscopic polyangiitis
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Microscopic polyangiitis is a vasculitis.[1] It preferentially attacks the kidneys and the lungs.
Manifestations
Common manifestations are:
- About 90% of patients have glomerulonephritis similar to Wegener's granulomatosis[1]
- About half may have pulmonary hemorrhage[1]
- About half may have peripheral neuropathy.[2]
Diagnosis
Laboratory
Anti-neutrophil cytoplasmic antibodies (ANCA) are usually elevated. Characteristically, there are no immunoglobulin deposits.
References
- ↑ 1.0 1.1 1.2 Bosch X, Guilabert A, Font J (2006). "Antineutrophil cytoplasmic antibodies.". Lancet 368 (9533): 404-18. DOI:10.1016/S0140-6736(06)69114-9. PMID 16876669. Research Blogging.
- ↑ Cattaneo L, Chierici E, Pavone L, Grasselli C, Manganelli P, Buzio C et al. (2007). "Peripheral neuropathy in Wegener's granulomatosis, Churg-Strauss syndrome and microscopic polyangiitis.". J Neurol Neurosurg Psychiatry 78 (10): 1119-23. DOI:10.1136/jnnp.2006.111013. PMID 17299018. Research Blogging.